Introduction
There’s something magical about the combination of creamy, cheesy pasta and the delicate sweetness of seafood. Imagine a cozy evening at home, perhaps with soft lighting and your favorite playlist in the background, the aroma of garlic and butter filling your kitchen. That’s exactly the inspiration behind these Shrimp and Crab Alfredo Lasagna Roll-Ups—a dish that takes comfort food to an indulgent, sophisticated level.

This recipe was born from a love of Italian-American cuisine with a seafood twist. While classic lasagna often sticks to tomato sauces and ground meats, I wanted something luxurious yet approachable, a dish that would make any dinner feel like a celebration. With tender lasagna sheets rolled around succulent shrimp, sweet crab meat, and a rich Alfredo sauce, each bite is a creamy, cheesy delight that melts in your mouth. Perfect for special occasions, family dinners, or simply when you want to treat yourself, these roll-ups are sure to become a new favorite.

The combination of flavors is perfectly balanced—the seafood offers a light sweetness, while the Alfredo sauce brings creaminess, and a sprinkle of Parmesan on top ensures a golden, bubbly finish. Even if you’ve never made lasagna roll-ups before, this recipe is straightforward and designed to impress both the cook and the diners.

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Why You’ll Love This Recipe

There are countless reasons to fall in love with this Shrimp and Crab Alfredo Lasagna Roll-Ups. First, they’re visually stunning—rolled lasagna noodles filled with creamy seafood, baked until golden, make for a dish that looks like it belongs in a restaurant. Second, the flavors are luxurious yet comforting, with layers of cheesy goodness and tender seafood. Third, it’s versatile: you can prepare it ahead of time, freeze it for later, or make it fresh for a weekend feast.

This recipe is perfect for anyone who loves Italian cuisine but wants to try something beyond traditional lasagna. The creamy Alfredo sauce complements the delicate seafood perfectly, while the lasagna noodles provide a hearty base that binds everything together. It’s the kind of dish that satisfies cravings for both indulgence and home-cooked comfort.

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Ingredients You’ll Need

To create this seafood-packed indulgence, you’ll need fresh and flavorful ingredients. Here’s what you’ll need:

• 12 lasagna noodles
• 1 pound large shrimp, peeled, deveined, and chopped
• 1 cup lump crab meat, picked over for shells
• 2 tablespoons olive oil
• 3 cloves garlic, minced
• 4 tablespoons unsalted butter
• 3 tablespoons all-purpose flour
• 2 cups whole milk
• 1 cup heavy cream
• 1 teaspoon salt
• ½ teaspoon black pepper
• ½ teaspoon nutmeg
• 1 cup grated Parmesan cheese, divided
• 1 cup shredded mozzarella cheese
• ½ cup ricotta cheese
• 2 tablespoons fresh parsley, chopped

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How to Make Shrimp and Crab Alfredo Lasagna Roll-Ups

Step 1: Cook the Lasagna Noodles

Bring a large pot of salted water to a boil. Cook the lasagna noodles according to the package instructions until al dente. Drain and lay the noodles flat on a baking sheet lined with parchment paper. Drizzle lightly with olive oil to prevent sticking.

Step 2: Prepare the Seafood Filling

In a medium skillet, heat 2 tablespoons of olive oil over medium heat. Add the garlic and sauté for 1–2 minutes until fragrant. Add the chopped shrimp and cook until pink and opaque, about 3–4 minutes. Remove from heat and stir in the crab meat, making sure the mixture is well combined but not overcooked.

Step 3: Make the Alfredo Sauce

In a saucepan, melt the butter over medium heat. Whisk in the flour to form a smooth roux and cook for 1–2 minutes. Gradually whisk in the milk and heavy cream, stirring constantly to avoid lumps. Season with salt, black pepper, and nutmeg. Cook until the sauce thickens, about 5–6 minutes. Stir in ½ cup of Parmesan cheese until melted and smooth.

Step 4: Assemble the Roll-Ups

Spread a thin layer of Alfredo sauce on each lasagna noodle. Spoon the shrimp and crab mixture evenly onto the noodles, then add small dollops of ricotta cheese. Roll each noodle tightly and place seam-side down in a greased baking dish.

Step 5: Bake to Perfection

Pour the remaining Alfredo sauce over the roll-ups, then sprinkle with mozzarella and the remaining Parmesan cheese. Bake in a preheated oven at 375°F (190°C) for 25–30 minutes, until the top is golden and bubbly. Garnish with fresh parsley before serving.

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Tips for Perfect Shrimp and Crab Alfredo Lasagna Roll-Ups

• Use fresh seafood: Fresh shrimp and crab will give your dish the best flavor. Avoid pre-cooked or frozen seafood if possible.
• Cook noodles al dente: Slightly undercooked noodles will finish baking perfectly in the oven and won’t become mushy.
• Make ahead: You can assemble the roll-ups a day ahead and refrigerate them, then bake just before serving.
• Customize cheeses: Feel free to experiment with different cheeses like Fontina or Asiago for a richer flavor.

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FAQs About Shrimp and Crab Alfredo Lasagna Roll-Ups

1. Can I make this recipe ahead of time?
Absolutely! One of the best things about this dish is its make-ahead potential. You can prepare the roll-ups and keep them covered in the refrigerator for up to 24 hours. When ready to serve, simply bake as directed, adding a few extra minutes if necessary since the dish will be cold from the fridge. This is perfect for planning a dinner party or a family meal in advance.

2. Can I freeze the roll-ups?
Yes! These lasagna roll-ups freeze beautifully. Assemble the dish as instructed but don’t bake it. Wrap the baking dish tightly with foil or plastic wrap and store it in the freezer for up to 2 months. When ready to enjoy, bake from frozen at 375°F (190°C), covering with foil for the first 40 minutes, then uncovering for the last 10–15 minutes to achieve a golden top.

3. Can I substitute the seafood?
Certainly! While shrimp and crab are classic and provide the perfect balance of flavor, you can use cooked lobster, scallops, or even a combination of vegetables like spinach, mushrooms, and roasted peppers for a vegetarian-friendly option. Just make sure the filling is well-seasoned and has a creamy texture to hold the roll-ups together.

4. How can I prevent the roll-ups from falling apart?
The key is layering the filling evenly and not overstuffing each noodle. Spread the filling thinly and roll tightly, placing them seam-side down in the baking dish. Using a slightly thicker Alfredo sauce also helps bind everything together, ensuring that your roll-ups stay intact when served.

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Serving Suggestions

These Shrimp and Crab Alfredo Lasagna Roll-Ups are a main dish on their own, but they also pair beautifully with a fresh side salad, garlic bread, or roasted vegetables. A crisp Caesar salad or lightly dressed arugula can provide a refreshing contrast to the rich, creamy roll-ups. For a touch of elegance, serve with a drizzle of extra Alfredo sauce and a sprinkle of fresh parsley or chives.

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Final Thoughts

There’s something truly comforting about this dish—it’s a perfect combination of creamy, cheesy indulgence and delicate seafood flavor. Whether you’re cooking for a special occasion or a quiet night in, these Shrimp and Crab Alfredo Lasagna Roll-Ups are bound to impress. They show that seafood doesn’t have to be complicated and that lasagna doesn’t always have to follow tradition.

The recipe strikes a beautiful balance between elegance and comfort. It’s rich and luxurious, yet approachable enough for a home cook to master without feeling overwhelmed. Plus, the ability to make it ahead of time, or even freeze for later, makes it practical as well as decadent.

Every bite delivers a creamy, cheesy explosion of flavor, from the tender lasagna noodles to the savory Alfredo sauce and the sweet, delicate shrimp and crab filling. It’s a dish that makes people smile, savor, and come back for seconds. Sharing this recipe is like sharing a piece of comfort, sophistication, and love in one glorious roll-up.

So, next time you want to treat yourself or your loved ones to a truly indulgent dinner, give this recipe a try. The effort is well worth it, and the results are nothing short of spectacular. Not only will you enjoy a decadent meal, but you’ll also create memories around the table, celebrating the joy of food, flavor, and family.

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